IL-13 rat rec.
€235.50
Product information "IL-13 rat rec."
IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.
This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
Interleukin-13 Rat Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 113 amino acids and having a molecular mass of 12.7 kDa. The IL-13 is purified by proprietary chromatographic techniques.
Synonyms: NC300, ALRH, BHR1, P600, IL-13
| Liquid / Powder: | Powder |
|---|---|
| Product Category: | Cytokines and Growth Factors |
| Size: | 2 µg |
| Sterile: | Yes |
| Storage: | See Datasheet |