IL-23 human rec.
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Product information "IL-23 human rec."
Interleukin 23 (IL-23) belongs to the IL-12 family and is produced by antigen presenting cells. IL-23 is composed of a subunit of the heterodimeric cytokine IL-23 and the p40 subunit of Interleukin 12 (IL-12B). IL-23 using IL-12RB1 and IL-23R (specific for IL-23) can activate STAT and NF-kB pathways and stimulate the production of interferon-gamma). IL-23 is known to take a vital part in the inflammation process and is associated with auto immune diseases. However, unlike IL-12, which acts primarily on naive CD4(+) T cells, IL-23 preferentially acts on memory CD4(+) T cells. IL-23 Human Recombinant produced in HEK cells is a 55kDa heterodimeric protein composed of 2 disulfide-linked subunits - 19kDa (p19) and 43 kDa (p40).
Synonyms: Interleukin 23 alpha subunit p19, Interleukin 12 subunit beta p40, CLMF2, CLMF p40, SGRF, IL23P19, IL-23-A, Interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, Interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte maturation factor 2 p40), NK cell stimulatory factor chain 2, Cytotoxic lymphocyte maturation factor 40 kDa subunit
| Liquid / Powder: | Powder |
|---|---|
| Product Category: | Cytokines and Growth Factors |
| Size: | 2 µg |
| Sterile: | Yes |
| Storage: | See Datasheet |