PDGF-AB human rec.
Product information "PDGF-AB human rec."
The term ’PDGF’ refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets. They act as potent mitogens for almost all mesenchyme-derived cells.
Aberrant expression is involved in certain cancers, fibro-proliferative disorders and atherosclerosis. The proteins also contribute to wound healing and neural regeneration. There are four members of the PDGF family – PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist – a short form that is soluble and a long form that is retained by the extracellular matrix.
PDGF AB human recombinant is a heterodimeric, non-glycosylated, polypeptide chain containing 234 amino acids consisting of 13.3 kDa alpha-chain and 12.2 kDa beta-chain having a total molecular mass of 25.5 kDa. PDGF-AB is purified by proprietary chromatographic techniques.
Synonyms: Glioma-derived growth factor, Osteosarcoma-derived growth factor
| Liquid / Powder: | Powder |
|---|---|
| Product Category: | Cytokines and Growth Factors |
| Size: | 10 µg |
| Sterile: | Yes |
| Storage: | See Datasheet |