RANK Ligand Soluble Mouse rec.
Product information "RANK Ligand Soluble Mouse rec."
RANKL binds to tnfrsf11b/opg and to tnfrsf11a/rank. Osteoclast differentiation and activation factor augments the ability of dendritic cells to stimulate naive T-cell proliferation. May be an important regulator of interactions between T-cells and dendritic cells and may play a role in the regulation of the T-cell-dependent immune response. sRANKL may also play an important role in enhanced bone resorption in humoral hypercalcemia of malignancy.
sRANKL murine recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 174 amino acids, having a total molecular mass of 19.9 kDa. CD254 is purified by proprietary chromatographic techniques.
Synonyms: TRANCE, TNF-related activation-induced cytokine; ODF, Osteoclast differentiation factor; TNFSF11, Tumor necrosis factor ligand superfamily member 11; CD254 antigen
Liquid / Powder: | Powder |
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Product Category: | Cytokines and Growth Factors |
Size: | 10 µg |
Sterile: | Yes |
Storage: | See Datasheet |