NGF-beta murine rec.
Product information "NGF-beta murine rec."
NGF-β has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
Nerve Growth Factor was the 1st protein found from the family of neurotrophic factors that influence the growth and differentiation of sympathetic and sensory neurons. NGF consists of 3 different subunits: α, β, and γ. The β subunit is accountable for its growth stimulating activity. The synthesis of NGF in astrocytes is enhanced by a range of cytokines such as IL1, TNF-α, PDGF & TGF-β.
Synonyms: Beta Polypeptide, NGF, NGFB, HSAN5, Beta-NGF, MGC161426, MGC161428
Liquid / Powder: | Powder |
---|---|
Product Category: | Cytokines and Growth Factors |
Size: | 20 µg |
Sterile: | Yes |
Storage: | See Datasheet |